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Gómez Almaguer David.
Adult patients with immune thrombocytopenic purpura.
New expectations
Med Univer 2014; 16(65)  : 219-221

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Introduction

Immune thrombocytopenic purpura (ITP) is an acquired autoinmune disorder involving antibody and cell mediated destruction of platelets. In acute cases the majority of patients have clinical bleeding and less than 30,000 platelets. Nowadays, there is enough evidence that immune destruction of circulating platelets and suppression of platelets production in the bone marrow is also happening.

Diagnosis is usually an easy task, requiring an isolated thrombocytopenia below 100×109/L, no other obvious cause for the condition and no clinically evident secondary form of immune thrombocytopenia. The incidence has geographic variation, but there are nearly 30 new cases per million annually, it is more prevalent in women and its incidence increases with age. Over 70% of affected children resolve spontaneously, whereas ITP in adults is a more complicated disease, typically having an insidious onset with no preceding viral or other illness and usually following a persistent or chronic course.


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