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Portopulmonary hypertension (PoPH) is a serious lung vascular complication of portal hypertension. Current definition criteria for PoPH include the following: • Presence of portal hypertension with or without cirrhosis. • Presence of pulmonary arterial hypertension (PAH) diagnosed by right heart catheterization (RHC); and absence of an alternative cause for PAH. Hemodynamic criteria for PAH, as based on RHC, must include a mean pulmonary arterial pressure (mPAP) ≥ 25 mmHg at rest, and pulmonary vascular resistance (PVR) > 240 dynes/sec/cm^-5 [PVR = mPAP - PAOP/cardiac output (CO) x 80] or > 3 Wood units (Wood units= mPAP – PAOP/CO). Ideally, pulmonary arterial occlusion pressure (PAOP) should be ≤ 15 mmHg, and whenever this criterion is not met, the transpulmonary gradient (TPG) must be > 12 mmHg, reflecting the presence of true PAH in association with venous hypertension.

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2014-10-30   |   451 visitas   |   Evalua este artículo 0 valoraciones

Vol. 13 Núm.6. Noviembre-Diciembre 2014 Pags. 719-721 Ann Hepatol 2014; 13(6)