Resumen

One of the most important successes of the human being in the last decades is the extent of their knowledge of space through research to keep the human body in microgravity during the spaceflight. In this article we review the literature on organic regions affected in an astronaut to continuous exposure that is involved, making a special emphasis on the cellular and molecular damage of their blood elements as there is the possibility of reproducing the effects of exposure to microgravity for evaluating the innate immune response and the condition of the bone marrow to study the neocytolysis (selective hemolysis of neocytes) and the presence of schistocytes and stomatocytes, occurring due to high levels of glutathione increases the rigidity of the erythrocyte membrane, which is favored by hidrostatic pressure changes, microviscosity and permeability, which may influence the transfer of oxygen. High concentrations of lactate contribute to an anaerobic condition, symptoms such as headache, nausea and malaise. In the process of readaptation to Earth occurs a stimulation of erythropoiesis aimed to maintain the optimal level of blood erythrocytes, necessary for the increased demand of oxygen in the tissues under the conditions of gravitation.

Palabras clave: Microgravity spaceflight neocytolysis.

2014-12-18   |   377 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.3. Julio-Septiembre 2014 Pags. 122-128 Rev Hematol 2014; 15(3)