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Dear Editor: Variceal hemorrhage (VH), particularly from esophageal varices, is associated with high fatality and recurrence rates in cirrhotics despite standard medical and endoscopic intervention. In primary sclerosing cholangitis (PSC), the decision to perform screening endoscopy varies. Retrospective studies suggest that platelet count negatively correlates with endoscopic features of portal hypertension, but assessment of the strength of this association requires further observational data as it is based on a relatively small number of patients with PSC. To further assess the relationship between platelet count and the presence of large (> 5 mm) esophageal varices in patients with PSC, and to determine the association between liver enzymes and model for end-stage liver disease score (MELD) with risk for large esophageal varices, we assessed all adult PSC patients seen at the University of Western Ontario over a 10 year period following approval by the Ethics Review Board.

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2016-06-23   |   228 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.1. Enero-Febrero 2016 Pags. 135-136 Ann Hepatol 2016; 15(1)