Fragmento

To The Editor, We would like to thank Basyigit, et al. for their comments of on our recent study that aimed to determine pretreatment 25(OH)D serum level among hepatitis C virus (HCV) infected individuals and its impact on virological response and laboratory data. Our main results were hepatitis C patients showed lower vitamin D level and it was associated to laboratory findings; however baseline 25(OH)D level was not independently associated with sustained virological response (SVR). We agree authors highlighting the influence of several serum interleukine level, vitamin D receptor (VDR) polymorphisms and malnutrition in vitamin D status and viral response to therapy with interferon and ribavirin. Unfortunately, these data were not available in our cohort. El Husseiny, et al found a negative correlation between vitamin D and serum level of IL-23 and IL-17 and MCP-1 in patients with hepatitis C genotype 4 suggesting vitamin D could be involved in immune response and fibrogenesis.

Palabras clave:

2016-06-23   |   175 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.1. Enero-Febrero 2016 Pags. 139-140 Ann Hepatol 2016; 15(1)