Resumen

Dear Editor: The natural history of non-alcoholic fatty liver disease (NAFLD) has yet to be fully defined. In the few relevant studies reported to date, repeat liver biopsies were performed in highly selected, predominantly non-alcoholic steatohepatitis (NASH) patients who may not reflect the general NAFLD population. Although newly developed, non-invasive means of documenting hepatic fibrosis will play an important role in providing natural history data, prospective studies implementing these techniques will take years and likely decades to complete. In the present study we employed reversal of serum alanine to aspartate aminotransferase (ALT/AST) > 1 ratios to determine the time fron initial presentation to development of advanced fibrosis/cirrhosis in adult NAFLD patients referred to our outpatient liver program between the years 1992-2012.

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2016-11-18   |   415 visitas   |   Evalua este artículo 0 valoraciones

Vol. 15 Núm.6. Noviembre-Diciembre 2016 Pags. 944-945 Ann Hepatol 2016; 15(6)