Evidence-Based Medicine and the Problem of Healthy Volunteers

Autores: Marchesini Giulio, Marchignoli Francesca, Petta Salvatore

Resumen

Healthy controls are subjects without the disease being studied but may have other conditions indirectly affecting outcome. In the present epidemics of obesity a few subjects with undiagnosed nonalcoholic fatty liver disease enter clinical studies as controls, producing biased results. Stricter selection criteria should be considered to prevent this risk.

Palabras clave: Clinical trials control group liver enzymes nafld obesity.

2017-12-13   |   354 visitas   |   Evalua este artículo 0 valoraciones

Vol. 16 Núm.6. Noviembre-Diciembre 2017 Pags. 832-834 Ann Hepatol 2017; 16(6)