Prevalence of frailty and its association with comprehensive geriatric assessment scores among older adults with hIV

Autores: Díaz Ramos Julio Alberto, Asencio del Real Gabriela, Fraga Ávila Claudia, Leal Mora David, González Hernández Luz Alicia, Andrade Villanueva Jaime Federico


Background: The number of older adults living with HIV (OALHIV) has increased significantly. Several similarities have been found between aging and HIV infection. Patients with HIV have premature complications observed only in chronological aging, usually called geriatric syndromes (GS): cognitive impairment, depressive symptoms, disability, nutritional risk, and frailty. The association between GS and the status of frailty in elderly adults with HIV is not yet clear. However, an effective strategy for the diagnosis of GS is the comprehensive geriatric assessment (CGA). Objectives: The objectives of this study were to determine the prevalence of frailty and its associations between CGA scores in OALHIV, attending HIV-AIDS clinics at a university-affiliated hospital in Mexico. Methods: A cross-sectional study in participants OALHIV, recruited between January 2015 and January 2017. Participants underwent a CGA, with which the diagnosis of frailty and GS was obtained. A multivariate linear regression analysis was determined to establish the association between CGA scores (disability, cognitive impairment, depression, and malnutrition) and frailty scores (FS). Results: We included 116 subjects; mean age was 55 years (standard deviation ± 6), women accounted for 20%. Overall, 14% were frailty. After adjusted, linear regression analyses showed that disability, cognitive impairment, depressive symptoms, and malnutrition scores explained 39% of the total variance of the FS (p < 0.0001). Conclusions: This study showed that the prevalence of frailty is higher in Mexican OALHIV. The combination of CGA scores can explain almost 40% of the variation in the dependent variable (FS). These results suggest that CGA can provide relevant information of health in the elderly community living with HIV.

Palabras clave: frailty HIV comprehensive geriatric assessment geriatrics syndromes.

2018-05-23   |   2,043 visitas   |   Evalua este artículo 0 valoraciones

Vol. 4 Núm.1. Enero-Junio 2018 Pags. 13-18 J Lat Am Geriatric Med 2018; 4(1)