Resumen

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease nowadays with currently no approved therapies for the disease. The liver plays a pivotal role in lipid and glucose metabolism. The interactions of molecular mechanisms on the gut for example influences the development still needs to be understood. Bile acids (BA) have been shown to impact metabolic homeostasis and insulin sensitivity. Here, we comment on a study analyzing BA profiles in NAFLD patients addressing novel pathways involved in NAFLD progression.

Palabras clave: NAFLD NASH bile acids steatosis microbiome.

2018-06-29   |   132 visitas   |   Evalua este artículo 0 valoraciones

Vol. 17 Núm.3. Mayo-Junio 2018 Pags. 341-342 Ann Hepatol 2018; 17(3)