Higher risk of uncontrolled disease and very poor glycemic control in younger patients with type 2 diabetes

Autores: López Navarro Juan M, Pérez Díaz Iván, Valladares Pérez Eduardo J, Sánchez Landa Elizabet, Staufert Gutiérrez Josette R, Vega Beyhart Arturo, Fagundo Sierra Reynerio

Resumen

Objective: This research aims to identify the risk factors associated with poor glycemic control in patients with Type 2 diabetes. Methods: A retrospective and transversal study was performed comprising patients with Type 2 diabetes mellitus who were classified into four groups according to glycated hemoglobin (HbA1c) level. Patients were considered to have good glycemic control when HbA1c was ≤ 7%. Clinical records were consulted to obtain clinical and laboratory information. Multivariate logistic regression analysis was performed to identify independent risk factors. Results: From the final sample (n = 204), associated risk factors for uncontrolled diabetes were < 60 years old (odds ratio [OR] 4.421; 95% confidence interval [CI], 1.991-9.817), < 7 years of education (OR 2.814; 95% CI: 1.337-5.926), ≥ 3 comorbidities (OR 3.556; 95% CI: 1.496-8.453), and history of hypoglycemia (OR 5.406; 95% CI: 1.477-19.790). Age < 50 years (OR 3.737; 95% CI: 1.403-8.357), body mass index > 25 kg/m2 (OR 23.830; 95% CI: 3.100-183.166), smoking (OR 4.511; 95% CI: 1.917-10.615), and history of diabetic ketoacidosis (OR 4.744; 95% CI: 1.061-21.210) were associated with HbA1c ≥ 12%. Conclusion: Uncontrolled disease is more prevalent in patients with low education, three or more comorbidities, and age < 60 years. Daily lifestyle factors, such as nutritional status and smoking, are associated with very poor glycemic control.

Palabras clave: diabetes risk factors glycemic control glycated hemoglobin.

2018-10-30   |   574 visitas   |   Evalua este artículo 0 valoraciones

Vol. 5 Núm.3. Julio-Septiembre 2018 Pags. 115-124 Rev Mex Endocrinol Metabol Nut 2018; 5(3)