Early acquisition of Pseudomonas aeruginosa

in Mexican children with cystic fibrosis 

Autores: Bustamante Adriana E, Mascareñas Martínez Lourdes, Fernández Lucia Teresa, González González Gloria M, Mercado Longoria Roberto


Introduction: chronic infection with Pseudomonas aeruginosa (P. aeruginosa) is associated with a greater deterioration of pulmonary function, increase in hospitalizations and shorter survival in patients with cystic fibrosis. Objectives: to evaluate the age of first detection of P. aeruginosa, effectiveness of the eradication treatment and prevalence of other pathogens in airway cultures. Materials and methods: a cohort of patients with CF diagnosed within first year of life, who had follow-up at University Hospital was studied. Respiratory cultures were obtained quarterly. Patients with infection by P. aeruginosa received eradication treatment. Results: thirty-five patients were included. During follow-up, 608 cultures were performed. In 34.7%, normal flora was detected, S. aureus 32.8%, P. aeruginosa 20.4%. Median age at first positive culture was 9 months. Eradication was achieved in 81.8%. Conclusions: in this cohort of patients with cystic fibrosis, the acquisition of P. aeruginosa is earlier than in other groups reported in literature.

Palabras clave: chronic infection pseudomonas aeruginosa cystic fibrosis eradication.

2020-08-17   |   162 visitas   |   Evalua este artículo 0 valoraciones

Vol. 41 Núm.4. Julio-Agosto 2020 Pags. 159-64 Acta Pediatr Méx 2020; 41(4)