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To the editor. Severe sepsis is a major cause of morbidity and mortality, affecting between 36,000 and 64,000 person-years in the United Kingdom, with a mortality rate of 35%. It is associated with activation of inflammatory and haemostatic systems that could lead to disseminated intravascular coagulation (DIC) and MODS (multiple organ dysfunction)2)
This massive and widespread microvascular thrombosis is associated with higher mortality rates *)
In sepsis, there are quite systems for grading severity. The SOFA score (Sequential Organ Failure Assessment), which determine severity level and development of organ failure, contemplates platelet count. These, decrease in sepsis.
Nevertheless, none of the scores includes the INR (International normalized ratio) nor Prothrombin time prolongation, to assess sepsis severity or the risk of die or develop DIC. This is a limitation.

Palabras clave: SEPSIS AND THROMBOSIS

2023-12-22   |   51 visitas   |   Evalua este artículo 0 valoraciones

Vol. 3 Núm.3. Julio-Septiembre 2017 Pags. 107- REM HRL 2017; 3(3)