Background: Delirium marked by its significant impact on mortality during the coronavirus disease 19 (COVID-19) pandemic, exhibits different biochemical parameters. Objective: The objective of this study was to identify differences in biochemical parameters among patients who developed delirium during hospitalization, with and without COVID-19. Methods: Retrospective single- center study, persons aged 65 and older with delirium were enrolled, comparing those with and without COVID-19. Analyses encompassed biochemical parameters, comorbidities, hospital stays, and 30-day mortality. Descriptive and inferential statistics were incorporated. Results: Among 157 delirium patients, 61 had COVID-19. The COVID-19 group, characterized by older age, higher sodium, and lower albumin levels, extended hospital stays, and higher mortality, exhibited a significant difference in 30-day mortality through Kaplan–Meier analysis. Cox regression revealed a negative association between lower albumin levels and increased mortality. In the subgroup analysis, non-COVID-19 patients with mortality displayed lower glucose and albumin levels and prolonged hospital stays compared to the survival group. COVID-19 patients with mortality had lower hemoglobin, hematocrit, and albumin levels; and higher potassium compared to the survival group. Conclusion: We identified biochemical differences between COVID-19 and non-COVID-19 patients with delirium. Lower albumin levels were associated with increased mortality in delirium across both populations.

Palabras clave: Delirium coronavirus disease 19 serum albumin

2024-06-18   |   35 visitas   |   Evalua este artículo 0 valoraciones

Vol. 10 Núm.1. Enero-Junio 2024 Pags. 027-033 J Lat Am Geriatric Med 2024; 10(1)