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Marrow transplantation from HLA-identical siblings has been increasingly adopted for therapy of non-malignant conditions. The first successful transplant in b-thalassaemia, was performed by Thomas et al. in 1981 in an untransfused 14-months old child. This patient, now aged 18 years, is the longest surviving patient who is definitely cured from a genetic disease by bone marrow transplantation. At the same time a 14-year old thalassemic patient who had recived 150 cell transfusions was transplanted in Pesaro but he had recurrence of thalassemia after rejection of the graft.

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2004-11-19   |   1,214 visitas   |   1 valoraciones

Vol. 136 Núm.2. Julio-Agosto 2000 Pags. 49-51 Gac Méd Méx 2000; 136(Supl. 2)