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Clinical Electrophysiology: Supraventricular Arrhythmias (Poster Session) Tuesday, March 14, 2006, 12:30 p.m.-4:00 p.m., Georgia World Congress Center, Hall B1 Abstract: 1015-126 Citation: Journal of the American College of Cardiology, Fe-bruary 21, 2006, Volume 47, Issue 4, Supplement A Biventricular Pacing Reduces Incidence of Microvolt T Wave Alternans in Patients With Congestive Heart Failure Safwat A. Gassis, Fernando Mera, Jonathan J. Langberg, David B. DeLurgio, Angel R. Leon, Paul F. Walter Carlyle Fraser Heart Center, Emory University, Atlanta, Geor-gia, United States Background: Microvolt T-Wave alternans (MTWA) is a useful non-invasive tool to asses risk for malignant ventricular arrhythmias. Cardiac resynchronization (CRT) with biventricular pacing (BiV) has been shown to improve hemodynamics and may reduce the risk of sudden cardiac death. The purpose of the current study was to determine the effect of CRT on MTWA. Methods: Twenty two patients underwent implantation of a CRT device (9 ischemic, mean ejection fraction 18 +/- 7%). MTWA was measured during atrial pacing, DDD pacing with only right ventricular (RV) activation, and during DDD pacing with biventricular pacing in an integrated bipolar configuration. Results: MTWA during atrial pacing was positive in 55%, negative in 27% and indeterminate in 18% of patients. MTWA results were dichotomized into negative and non-negative categories. BiV pacing increased the incidence of negative MTWA from 27% with atrial pacing to 64%. Overall MTWA concordance between atrial and BiV pacing was 55% whereas concordance between atrial and RV pacing was 73%. Concordance of atrial or RV pacing with BiV pacing was 44% for positive or indeterminate tests compared to 83% for negative MTWA tests.

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2008-06-11   |   702 visitas   |   Evalua este artículo 0 valoraciones

Vol. 1 Núm.1. Enero-Marzo 2006 Pags. 52-55 Rev Insuf Cardíaca 2006; I(1)