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Typhoid fever, caused by Salmonella enterica serovar Typhi (S. Typhi), remains a major cause of enteric disease and a significant public health problem, predominantly in children in developing countries. Global estimates of typhoid fever range from 17 to 22 million cases per year with an associated 216,000 to 600,000 deaths annually [1,2]. This lower estimate is based on a conservative case fatality rate of 1%, (CRF range varies from 1% to 4%); yet the number of typhoid-related deaths each year is comparable to that of other diseases that are considered top priorities for disease control in the global health community, including cervical cancer caused by HPV, and is greater than others such as Japanese encephalitis and meningococcal meningitis.

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2008-09-21   |   519 visitas   |   Evalua este artículo 0 valoraciones

Vol. 2 Núm.4. Agosto 2008 Pags. 250-252. J Infect Developing Countries 2008; 2(4)