Resumen

Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64mg/ml. Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.

Palabras clave: Enteric fever Salmonella Typhi drug resistance.

2008-09-21   |   753 visitas   |   Evalua este artículo 0 valoraciones

Vol. 2 Núm.4. Agosto 2008 Pags. 324-327. J Infect Developing Countries 2008; 2(4)