Resumen

Introduction: With the increasing prevalence of bloodstreams infections caused by Candida sp. is necessary to establish the susceptibility of resistant strains in various geographical regions. Objective: To determinate the in vitro susceptibility to fluconazole, itraconazole, voriconazole and amphotericin B in yeasts isolated from blood through E Test method. Material and methods: In the period from 1992 to 2007; a total 112 strains of Candida species were isolated from blood on patients at the Instituto Nacional de Cardiología Ignacio Chávez. Suceptibility of these strains was performed to know the level of resistance to Itraconazole, fluconazole, voriconazole and amphotericin B by E test method. Results: C. albicans was the most common species (60.2%), followed by C. tropicalis (9.8%). A five percent of resistance to itraconazole, 1.8% to fluconazole; and 0.9% to amphotericin B and voriconazole were found. C. glabrata was the most resistant species to the four antifungal agents. Conclusions: The yeasts resistance to the four antifungal agents is still lower in our patients.

Palabras clave: Candida fluconazole itraconazole amphootericin B voriconazole.

2009-12-17   |   922 visitas   |   Evalua este artículo 0 valoraciones

Vol. 61 Núm.4. Julio-Agosto 2009 Pags. 294-299 Rev Invest Clin 2009; 61(4-ENGLISH)