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Reply: We thank Dr. De Mattos for their interest in our study. Many attempts have been performed to find comfortable and cost-effective methods different from endoscopy for diagnosing esophageal varices. These non-invasive approaches include, among others, the following: platelet count; spleen diameter; platelet count and Child-Pugh score; spider angiomata, ALT and albumin; CT esophageal study; fibrotest ((c-glutamyltranspeptidase, haptoglobin bilirubin, apolipoprotein A, alpha-2-macroglobulin); and fibroscan (transient elastography). We are fully aware of the limitations of these predictors, but among all of these methods, platelet count/spleen diameter ratio has been one of the most consistently evaluated. This ratio has been developed by Gianini, et al. by combining 2 portal hypertension-dependent variables that can potentiate its accuracy on predicting esophageal varices.

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2010-07-19   |   712 visitas   |   Evalua este artículo 0 valoraciones

Vol. 9 Núm.3. Julio-Septiembre 2010 Pags. 303-304 Ann Hepatol 2010; 9(3)