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Non-alcoholic fatty liver disease and the metabolic syndrome in an urbran hospital serving an African community Onyekwere C.A, et al. The term nonalcoholic fatty liver disease (NAFLD) is used to describe a spectrum of histologic findings ranging from simple steatosis to nonalcoholic steatohepatitis with progressive fibrosis. Diabetes, obesity and metabolic syndrome are risk factors for NAFLD, and it is present in 50% of diabetics and 76% of obese individuals. In a large population based cohort study, NAFLD was detected in one third of the American adults. In this issue, Onyekwere, et al., present data on the prevalence of NAFLD in Nigeria, and compare the prevalence of the disease in the diabetic and non-diabetic subjects. This prospective cross sectional study was carried out in an endocrinology clinic of an urban university teaching hospital in Lagos, Nigeria. One hundred and fifty subjects were recruited from October 2009 to August 2010, 106 were diabetics and 44 non-diabetics, with the latter group serving as the comparator group. A questionnaire on liver disease symptoms and physical examination were undertaken. Blood work including fasting blood sugar and lipid profile, liver biochemistry, hepatitis B and C virus serology were collected and all subjects had an upper abdominal ultrasound scan to determine the radiological prevalence of fatty liver.

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2011-03-30   |   573 visitas   |   Evalua este artículo 0 valoraciones

Vol. 10 Núm.2. Abril-Junio 2011 Pags. 115-118 Ann Hepatol 2011; 10(2)