Resumen

Despite intensive control efforts over the past decades, Brazil still accounts for more than 50% of the malaria burden in the Americas and the Caribbean, with 458,041 slide-confirmed cases reported countrywide in 2007. The reason malaria has proved so difficult to control in this middle-income country with a reasonable health infrastructure remains unclear. Here we examine whether four strategies that were largely successful in other countries (aggressive active case detection, improved anti-relapse therapy for P. vivax infections, distribution of insecticide-treated bed nets, and selective house spraying with residual insecticides) are likely to work in Brazil. We review evidence fron field and laboratory studies and identify gaps in our knowledge that require further investigation with well-designed large-scale trials.

Palabras clave: Malaria control Brazil Amazonia Plasmodium falciparum Plasmodium vivax.

2011-04-19   |   225 visitas   |   Evalua este artículo 0 valoraciones

Vol. 4 Núm.9. Septiembre 2010 Pags. 533-545. J Infect Developing Countries 2010; 4(9)