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Induced pluripotent stem cells (iPSC) were first described in 2006. The journal Science stated the following year in the December 19 issue, that the methodology employed for their production, was the years breakthrough. The iPSC are genetically reprogrammed adult cells, converted to embryonic stem cells (ESC), which can become any cell type and tissue of the organism with the proper stimulus. This capability is the goal of therapeutic cloning which aims to use laboratory grown tissues to treat patients with various degenerative processes for which there is no present day treatment, like Alzheimer’s and Parkinson’s diseases or type 1 diabetes, amongst others. The problem with ESC is that their most common sources are: • Surplus embryos fro m assisted fertility efforts. • Embryos made for the purpose by the procedure known as nuclear transfer, consisting in introducing to an enucleated ovocyte a somatic cell nucleus, which after a few days in culture produces a blastocyst like structure, fro m which it is possible to obtain around 150 ESC.

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2011-05-09   |   566 visitas   |   Evalua este artículo 0 valoraciones

Vol. 62 Núm.5. Septiembre-Octubre 2010 Pags. 396-397 Rev Invest Clin 2010; 62(5-ENGLISH)