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Recently an entire issue of Science (Vol. 298, No. 5591, 4 October 2002) was dedicated to the genomic description of the world’s foremost malaria vector, Anopheles gambiae. This was a momentous and pivotal event in medical entomology, both for the feat itself of delineating and annotating the genomic sequences of a deadly mosquito menace, but also for its implications for the field of medical entomology-ranging from insights into evolutionary relationships among diverse taxa to a better understanding of more pragmatic considerations of insecticide resistance and perhaps genetic engineering. The mass of accumulated information was staggering. The central article was accompanied by a foldout illustrating sequences, genes and genomic themes down to a 10 kb resolution, as well as an itemization of the accomplishments and limitations of the current presentation of the genomic organization. Six related research articles and reports described: 1) homology with the more distantly related Drosophila melanogaster, already fully sequenced; 2) homologies with closely related anopheline, Anopheles funestus; 3) immunity-related gene families; 4) evolution of insecticide resistance; 5) neuropeptides of A. gambiae; and 6) comparison of sensory protein lineages in A. gambiae and D. melanogaster.

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2012-05-11   |   304 visitas   |   Evalua este artículo 0 valoraciones

Vol. 22 Núm.4. Octubre-Diciembre 2002 Pags. 453 Biomédica 2002; 22(4)