Resumen

This study details our series of intracranial epidermoid cysts. A historical cohort of 110 epidermoid cysts that were excised from intracranial location over a 16 year period was reviewed. The incidence of epidermoid cysts, clinico- pathological examinations and cyst recurrence rate were noted. 110 cases were included in this study. 60 were males and 52 were females. The range aged was 15-74 years, mean 36.36 ± 13.45 for males and 34.20 ± 12.17 for female. Their locations included; supratentorial region (n=20), cerebello pontine angle (n=46), Middle ear (n=34), intraventricular and intraparenchymal (n=3), and one in cistern magnum, pineal region, retoclival, medular and mesencephalic region. Surgical exeresis was performed in all cases, partial in 25(26%) cases and total in 71 cases. 74% of the patients had a good prognosis and just 10(10.4%) cases had bad one. There was correlation between tumor size papillomatosis (p = 0.002), inflammation, and granuloma formation p = 0.000 respectively), between older patients and dyskeratosis (p = 0.008) and with the presence of dystrophic calcifications and longer follow-up (p = 0.013). Aseptic meningitis occurred postoperatively in 4 cases, recurrence of tumor was in 22 (20%) cases, two patients died and the rest of the cases had a satisfactory outcome. Conclusions: Recurrent leakage of the irritating cyst contents and subsequent chemical inflammatory response may be responsible for recurrence, high-density on CT scans and the cystic nature.

Palabras clave: Brain tumors Epidermoid Cyst Epidemiology Clinicopathological correlation.

2013-01-16   |   516 visitas   |   Evalua este artículo 0 valoraciones

Vol. 50 Núm.3. Julio-Septiembre 2012 Pags. 182-189 Patología 2012; 50(3)