Isolation frequency and susceptibility patterns of Nocardia species at a tertiary hospital laboratory in Karachi, Pakistan

Autores: Bibi Safia, Irfan Seema, Zafar Afia, Khan Erum

Resumen

Nocardia species are ubiquitous, fine, soil-borne aerobic filamentous actinomycetes that are Gram positive and weakly acid fast. Nocardiosis is an important opportunistic infection caused by Nocardia species. The infection most often occurs in immunocompromised individuals, especially those deficient in cell-mediated immunity but cases of nocardiosis have also been reported in some immunocompetent individuals. Person-to-person transmission of Nocardia has not been reported in the literature and the organism is usually considered to be acquired from the environment. Pulmonary nocardiosis and traumatically induced local abscesses are the common clinical manifestations of infection although rare cases of bacteremia, peritonitis, and corneal ulcers due to Nocardia species have also been reported. Clinical diagnosis of nocardiosis is often difficult and misleading because of its relative low incidence and lack of pathognomonic symptoms; hence the diagnosis is usually based on the isolation of the organism in pure culture from the affected area.

Palabras clave: Nocardia; sensitivity pattern; Co-trimaxazole; Pakistan.

2013-02-06   |   419 visitas   |   Evalua este artículo 0 valoraciones

Vol. 5 Núm.6. Junio 2011 Pags. 499-501 J Infect Developing Countries 2011; 5(6)