Effect of phlebotomy on motor UPDRS score, pain and medication dosage in a patient with parkinson's disease and hemochromatosis

Autores: Martínez KP, Eivaz Mohammadi S, González Ibarra Fernando Pavel

Resumen

Parkinson's disease (PD) is a slowly progressive neurodegenerative disorder associated with loss of dopaminergic neurons in the substantia nigra, some theories regarding the causes of PD include: environmental factors, genetic factors and oxidative stress induced by iron, copper, lipids, and proteins. We present a 43-year-old man with a past medical history of hemochromatosis, hypothyroidism and Parkinson's disease with a modest improvement over a course of two years under maximum doses of parkinsonism medications. After the patient initiated phlebotomy to treat hemochromatosis, significant improvement was noted in movement, gait, pain as well as a decrease in Motor UPDRS score and medication dosage. Phlebotomy may reduce motor impairment, pain and decrease medication dosage in a patient with PD and hemochromatosis.

Palabras clave: Parkinson's disease hemochromatosis phlebotomy UPDRS.

2013-04-19   |   834 visitas   |   Evalua este artículo 0 valoraciones

Vol. 6 Núm.4. Octubre-Diciembre 2012 Pags. 118-120 Arch Salud Sin 2012; 6(4)