Community-acquired CTX-M-15-type ESBL-producing Escherichia coli meningitis:

A case report and literature review 

Autores: Elaldi Nazif, Gozel Mustafa G, Kolayli Fetiye, Engin Aynur, Celik Cem, Bakici Mustafa Z, Vahaboglu Haluk

Resumen

In this report, a case of community-acquired acute bacterial meningitis (CA-ABM) caused by CTX-M-15-producing Escherichia coli in an elderly male patient was presented in the light of literature. Cultures of cerebrospinal fluid, blood, ear discharge and stool samples yielded CTX-M-15-producing E. coli in-vitro, which was resistant to the extended-spectrum cephalosporins and ciprofloxacin and susceptible to imipenem, meropenem and amikacin. Meningitis was treated with parenteral meropenem plus parenteral and intraventricular amikacin administration. Since bacterial meningitis is a life-threatening infection, empiric antibiotic therapy with carbapenem can be started before the culture results are obtained, mainly in areas where the ESBL epidemiology is well known.

Palabras clave: Escherichia coli; CTX-M-15; meningitis.

2013-05-23   |   457 visitas   |   Evalua este artículo 0 valoraciones

Vol. 7 Núm.5. Mayo 2013 Pags. 424-431 J Infect Developing Countries 2013; 7(5)