Severe hepatitis induced by cyproterone acetate: role of corticosteroids.

A case report 

Autores: Abenavoli Ludovico, Milic Natasa, Beaugrand Michel

Resumen

Cyproterone acetate (CPA) is an oral anti-androgen commonly used to treat advanced prostate cancer. A variety of hepatotoxic reactions has been reported with CPA. Here we describe a case of a male patient who developed severe drug-induced hepatotoxicity during the treatment with CPA. The case, presenting sub-acute hepatitis, was characterized by a rapid evolution of cirrhosis and a protracted activity during the period of a few months despite the treatment withdrawal and an apparent benefits of corticosteroids, suggesting their indication in life threatening cases.

Palabras clave: Hepatotoxicity interface hepatitis prednisone budesonide.

2013-07-09   |   307 visitas   |   Evalua este artículo 0 valoraciones

Vol. 12 Núm.1. Enero-Febrero 2013 Pags. 152-155 Ann Hepatol 2013; 12(1)