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Introduction The Pseudomonas aeruginosa is well-known cause of hospital infections with high morbidity and mortality rates. According to the National Nosocomial Infections Surveillance System (NNISS), P. aeruginosa is responsible for approximately 8% of all hospital infections. It was the most frequent cause of ventilator-associated pneumonias (VAP), the fourth-rated on the list of causes of hospital urinary infections, and fifth cause of surgical site infections according to frequency of occurrence. Infections caused by P. aeruginosa are difficult to control and treat due to its high rate of resistance to antibiotics and to the limited number of available antibiotics with efficacy against P. aeruginosa. During the last decade, an increase in resistance to imipenem and meropenem was observed among many strains of Gram-negative bacteria, and especially among isolates of P. aeruginosa. Numerous studies have also shown that carbapenem-resistant P. aeruginosa (CRPA) is frequently simultaneously resistant to other anti-pseudomonal antibiotics, making the treatment very difficult.

Palabras clave: P. aeruginosa; carbapenem resistance; risk factors.

2013-09-17   |   529 visitas   |   Evalua este artículo 0 valoraciones

Vol. 7 Núm.9. Septiembre 2013 Pags. 686-690 J Infect Developing Countries 2013; 7(9)