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Dear Editor: Nontyphoidal Salmonellae (NTS) are attracting increasing attention as a cause of invasive disease among African children and HIV-infected individuals. However, these invasive (hence iNTS) infections continue to cause confusion, partly because of the contrasting clinical presentations of NTS disease in high- and low-income countries. NTS in US and Europe normally cause self-limiting gastroenteritis. In sub-Saharan Africa, they cause bacteremia with symptoms of gastroenteritis in under half of patients. Case fatality rates for NTS bacteremia are 20-25%, multidrug resistance is increasing, and no vaccine is available.

Palabras clave: Nontyphoidal Salmonella; bacteremia; diarrhea; whole genome sequencing; genomics.

2014-02-14   |   389 visitas   |   Evalua este artículo 0 valoraciones

Vol. 8 Núm.2. Febrero 2014 Pags. 252-253 J Infect Developing Countries 2014; 8(2)