Acute genital ulcer associated with erythema nodosum

What should the first suspicion be? 

Autor: Husein-El Ahmed Husein

Fragmento

A 66-year-old woman presented to our department with a 9-month history of ulcers located in her genital region. She had a two-year history of repeated oral aphthae and erythema nodosum. Use of acyclovir treatment did not lead to good response. Behcet’s disease is a chronic, relapsing, inflammatory disease characterized by oral aphthae, genital ulcers, non-bacterial folliculitis, uveitis and erythema nodosum. The diagnosis of this condition is based on clinical criteria, as there is as yet no pathognomonic test, and mucocutaneous lesions, which are prominent in the presentation and diagnosis, may be considered the diagnostic hallmarks. Its prevalence varies very much, with higher rates in the so-called “silk route” countries: 80-370/100,000 in Turkey and 30/100,000 in Japan. In contrast, in Europe and the USA, the rate is 0.1-7.5/100,000. Genital ulcers are one of the main components of this complex condition, as they represent the second most common sign after oral aphthae, occurring in 57-93% of cases. Genital ulcers are characterized by clear demarcation and great depth. They are painful, they show a scarring tendency and they are usually resistant to local treatments.

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2014-03-04   |   531 visitas   |   Evalua este artículo 0 valoraciones

Vol. 34 Núm.1. Enero-Marzo 2014 Pags. 13-14 Biomédica 2014; 34(1)